See If You Qualify

Don’t face the journey with lymphoma alone.

The journey with lymphoma shouldn’t be a lonely one—join a growing community of people seeking answers through clinical research.

What is lymphoma?

Lymphoma is the most common type of blood cancer,1 and there is still a need to find treatments that work for all of those affected by it. If you or a loved one have lymphoma, you may be able to take part in a clinical research study.

Source: [1] https://lymphoma.org/aboutlymphoma/

See If You Qualify

Want to talk to your doctor about lymphoma clinical research?

Download the Patient-Doctor Discussion Guide.

Download Discussion Guide

About Lymphoma

Lymphoma is a type of cancer that affects white blood cells called lymphocytes. Lymphocytes help your body fight bacteria and viruses. In most cases, lymphomas develop when a change, also called a mutation, happens within a lymphocyte. This mutation causes the abnormal cell to replicate and live longer than a normal lymphocyte. These mutated, or cancerous, lymphocytes travel through the blood just like normal lymphocytes. As a result, they can spread and grow in other parts of the body.2

There are several different types of lymphomas, and how they are categorized often depends on the type of white blood cell affected:

Hodgkin lymphoma (HL): HL is a relatively uncommon form of lymphoma that involves the presence of Reed-Sternberg cells.3 There are 5 types of HLs.2

Non-Hodgkin lymphoma (NHL): Any lymphoma that does not involve Reed-Sternberg cells is categorized as a non-Hodgkin lymphoma. There are more than 90 types of NHLs overall.2

Quick Facts on Non-Hodgkin Lymphoma2

Read More

Quick Facts on Diffuse Large B-Cell Lymphoma

Read More

Quick Facts on Follicular Lymphoma

Read More

Quick Facts on Burkitt Lymphoma

Read More

Quick Facts on Mantle Cell Lymphoma (MCL)12

Read More

Sources: 

[2] https://lymphoma.org/aboutlymphoma/

[3] https://www.cancer.gov/publications/dictionaries/cancer-terms/def/reed-sternberg-cell

[4] https://lymphoma.org/aboutlymphoma/nhl/dlbcl/

[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142492/

[6] https://lymphoma.org/wp-content/uploads/2023/06/LRF_DLBCL_Fact_sheet.pdf

[7] https://www.nature.com/articles/s41598-020-71579-6

[8] https://www.cancer.gov/types/lymphoma/patient/adult-nhl-treatment-pdq

[9] https://www.nature.com/articles/modpathol201350 

[10] https://lymphoma.org/wp-content/uploads/2022/07/LRF_Burkitt_Lymphoma_Fact_Sheet.pdf

[11] https://www.nejm.org/doi/full/10.1056/NEJMe2118899

[12] https://rarediseases.org/rare-diseases/mantle-cell-lymphoma

Quick Facts on Burkitt Lymphoma

  • Burkitt lymphoma is a non-Hodgkin lymphoma (NHL). It is also a B-cell lymphoma because it affects the B-lymphocytes. Lymphocytes help your body fight infections.
  • There are 3 main types of Burkitt lymphoma: endemic, sporadic, and immunodeficiency-associated.10
  • The most common type in the United States and Europe is sporadic, and it accounts for 30–50% of childhood lymphomas.11
  • Burkitt lymphoma is a highly aggressive NHL, which means that it progresses quickly. It may affect the jaw, bones of the face, bowel, kidneys, and ovaries. In some cases, it may spread to the central nervous system (the brain and spinal cord) and/or bone marrow.10, 11
  • Although it can occur at any age, Burkitt lymphoma typically affects younger patients and is the most common type of pediatric NHL.10

Quick Facts on Non-Hodgkin Lymphoma2

  • Non-Hodgkin lymphoma (NHL) affects the lymphatic system, which includes a network of vessels, nodes, and ducts that help to maintain body fluid levels and remove cellular waste. It is more common than HL.
  • There are two broad categories of NHLs:
  • B-cell lymphomas (which account for about 85% of all NHLs)
  • T-cell lymphomas (which account for about 15% of all NHLs)
  • In terms of growth, NHLs are broken down into two categories:
  • Indolent = slow-growing
  • Aggressive = fast-growing
  • There are more than 90 types of NHLs overall. Although NHLs have traits in common, they may have different growth patterns, different appearances under a microscope, and different responses to treatment.
  • Symptoms include swollen lymph nodes, fever, night sweats, fatigue, and weight loss.

Great—let’s get you back to the homepage.

Back to Home

Quick Facts on Mantle Cell Lymphoma (MCL)12

  • Mantle cell lymphoma is a rare form of B-cell non-Hodgkin lymphoma (NHL). It is considered a B-cell lymphoma because it affects the B-lymphocytes. Lymphocytes help your body fight infections.
  • This rare condition affects only about 1 in 200,000 people each year.
  • Within lymph nodes, there are compartments called lymphatic nodules. There is a ring of small lymphocytes that surround the center of each nodule—this is the mantle zone. With MCL, your body overproduces lymphocytes in the mantle zone.
  • MCL is an aggressive NHL, which means that it progresses quickly. It typically affects older adults between 60 and 70 years old.
  • The most common symptoms of MCL include swollen lymph nodes, fatigue, night sweats, fever, and unexplained weight loss.
  • MCL is typically diagnosed through a combination of physical examination, blood tests, imaging studies, and a lymph node biopsy.

Quick Facts on Follicular Lymphoma

  • Follicular lymphoma is a type of cancer that affects white blood cells called B-lymphocytes. Lymphocytes help your body fight infections.
  • Follicular lymphoma is a non-Hodgkin lymphoma (NHL). It is also a B-cell lymphoma because it affects the B-lymphocytes.
  • Follicular lymphoma accounts for 20–40% of all NHLs in Western Europe and the United States.7
  • Follicular lymphoma is an indolent NHL, which means that it progresses slowly. People with follicular lymphoma may not notice any obvious symptoms of it.
  • Symptoms include swollen lymph nodes (especially in the part of the body where the lymphoma starts to grow), fever, night sweats, fatigue, and weight loss.8
  • Incidence of follicular lymphoma increases with age, and it is the most common form of indolent NHL.9

Quick Facts on Diffuse Large B-Cell Lymphoma

  • Diffuse large B-cell lymphoma (DLBCL) is the most common of all NHLs worldwide.4
  • DLBCL is considered an aggressive or fast-growing NHL. It is also a B-cell lymphoma because it affects white blood cells called B-lymphocytes. Lymphocytes help your body fight infections.
  • Although DLBCL can affect children, and is one of the most common NHL subtypes in children,5 people over the age of 60 are most commonly affected by DLBCL.4
  • For many with DLBCL, the first symptom is rapid swelling in the neck, underarms, or groin. The swelling is caused by enlarged lymph nodes.6
  • Treatment will depend on the subtype of DLBCL. For example, there are subtypes that mostly occur in younger patients and affect the chest cavity, while there are other subtypes that only affect the brain.6